Common problems and errors when establishing IVIVC
How to predict concentrations
Utilization of IVIVC
Specific cases 1
Specific cases 2
Benefits of attending
Get critical insights into the types of IVIVC
Understand the selection of most appropriate data to establish IVIVC
Familiarize yourself with predictability
Learn when IVIVC could & could not be established
Gain clarification on intersubject & intrasubject variability
Explore absorption determination
Understand what to do in absence of IR or IV
Learn how to establish time scaling, classical and inverse of release function
Two stage approach level A and Level C approach, examples on applications for MR formulations, class 2 drugs, metabolites, etc...
Alternative approach convolution through deconvolution methods, example on Long-acting implants
Specific case, discuss ways to apply IVIVC for DR formulations, Inhaled products
Gain tips for pooling data from more than one study
Explore setting dissolution limits
Understand utilization of IVIVC in development, variations, optimization
Valuable experience in getting information for improvement of working procedures.
Ivana Bušljeta PrusacBelupo
I found the training informative and productive and would recommend it to the specialists involved in the IVIVC studies. It is important that the trainer adjusted to the audience and aimed examples according to the needs of the attendees.